Dr. Wei Chen


Senior Scientist, Group Leader


Robert-Rössle-Strasse 10

13125 Berlin-Buch

Tel: +49-30-9406-2995

Fax: +49-30-9406-3068

Email: Wei.Chen(at)mdc-berlin.de

Research ID: C-1273-2011

ORCID: 0000-0003-3263-1627


  • until 10/2006: PhD in Molecular Genetics, Max Planck Institute for Molecular Genetics, Berlin, Germany
  • 07/2002: Master of Science in Medical Genetics, Sichuan University, Chengdu, China
  • 07/1993: Bachelor of Science in Biochemistry, Xiamen University, Xiamen, China



  • 2009 - present: Group Leader of the Scientific Genomics Platform, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine (MDC), Berlin, Germany
  • 2007 - 2009: Group Leader, Max Planck Institute for Molecular Genetics, Berlin, Germany
  • 2002 - 2006: Ph.D. student, Max Planck Institute for Molecular Genetics, Berlin, Germany
  • 1999 - 2002: Master student, Sichuan University, Chengdu, China
  • 1993 - 1999: Research Scientist, Sichuan University, Chengdu, China


Selected Publications:

  • Sun W, You X, Gogol-Döring A, He H, Kise Y, Sohn M, Chen T, Klebes A, Schmucker D, Chen W. Ultra-deep profiling of alternatively spliced Drosophila Dscam isoforms by circularization-assisted multi-segment sequencing. EMBO J. 2013 Jun 21. doi: 10.1038/emboj.2013.144. [Epub ahead of print]
  • Li N, You X, Chen T, Mackowiak SD, Friedländer MR, Weigt M, Du H, Gogol-Döring A, Chang Z, Dieterich C, Hu Y, Chen W.Global profiling of miRNAs and the hairpin precursors: insights into miRNA processing and novel miRNA discovery. Nucleic Acids Res. 2013 Feb 8. [Epub ahead of print]
  • Schwanhäusser B, Busse D, Li N, Dittmar G, Schuchhardt J, Wolf J*, Chen W*, Selbach M*. (2011 ) Global quantification of mammalian gene expression control. Nature. 2011 May 19;473(7347):337-42
  • Adamidi C, Wang Y, Gruen D, Mastrobuoni G, You X, Tolle D, Dodt M, Mackowiak SD, Gogol-Doering A, Oenal P, Rybak A, Ross E, Alvarado AS, Kempa S*, Dieterich C*, Rajewsky N*, Chen W * (2011) De novo assembly and validation of planaria transcriptome by massive parallel sequencing and shotgun proteomics. Genome Res 21(7):1193-200
  • Hu H, Wrogemann K, Kalscheuer V, Tzschach A, Richard H, Haas SA, Menzel C, Bienek M, Froyen G, Raynaud M, Van Bokhoven H, Chelly J, Ropers H, Chen W. (2010) Mutation screening in 86 known X-linked mental retardation genes by droplet-based multiplex PCR and massive parallel sequencing. The HUGO Journal: Volume 3, Issue 1, Page 41.
  • Chen W, Ullmann R, Langnick C, Menzel C, Wotschofsky Z, Hu H, Döring A, Hu Y, Kang H, Tzschach A, Hoeltzenbein M, Neitzel H, Markus S, Wiedersberg E, Kistner G, van Ravenswaaij-Arts CM, Kleefstra T, Kalscheuer VM, Ropers HH. (2009) Breakpoint analysis of balanced chromosome rearrangements by next-generation paired-end sequencing. Eur J Hum Genet. 18(5):539-43
  • Kuss AW, Chen W (2008) MicorRNAs in brain function and disease. Curr Neurol Neurosci Rep. 8(3):190-7.
  • Chen W, Kalscheu V, Tzschach A, Menzel C, Ullmann R, Schulz M, Erdogan F, Li N, Kijas Z, Arkesteijn G, Pajares IL, Goetz-Sothmann M, Heinrich U, Rost I, Dufke A, Grasshoff U, Glaeser BG, Vingron M, Ropers HH. (2008) Mapping translocation breakpoints by next-generation sequencing. Genome Research 18(7):1143-9


A complete CV can be found here: Wei Chen's CV